Перегляд за автором "Kropyvko, S.V."

Сортувати за: Порядок: Результатів:

  • Alternatively spliced short and long isoforms of adaptor protein intersectin 1 form complexes in mammalian cells 
    Gubar, O.S.; Kropyvko, S.V.; Tsyba, L.O.; Gasman, S.; Rynditch, A.V. (Вiopolymers and Cell, 2012)
    Intersectin 1 (ITSN1) is an adaptor protein involved in membrane trafficking and cell signaling. Long and short isoforms of ITSN1 (ITSN1-L and ITSN1-S) are produced by alternative splicing. The aim of our study was ...
  • Ca/calmodulin-dependent phosphorylation of endocytic scaffold ITSN1 
    Morderer, D.Ye.; Nikolaienko, O.V.; Skrypkina, I.Ya.; Rymarenko, O.V.; Kropyvko, S.V.; Tsyba, L.O.; Rynditch, A.V. (Вiopolymers and Cell, 2014)
    ITSN1 is an endocytic scaffold protein with a prominent function in synaptic transmission. It is known that Ca signaling is crucial for the regulation of synaptic proteins functioning. Aim. Checking the possibility of ...
  • Expression of ITSN2 and TKS5 in different subtypes of breast cancer tumors 
    Kropyvko, S.V.; Tsyba, L.O.; Novokhatska, O.V.; Nemesh, Y.M.; Syvak, L.A.; Tarasenko, T.Ye.; Grabovoy, A.N.; Rynditch, A.V. (Вiopolymers and Cell, 2019)
    Aim. Regardless a great progress in treatment, 15% of breast cancer cases remain lethal. One of the main problems in diagnosis and cure of this cancer type is its high clinical and genetic heterogeneity, and the identification ...
  • Identification and functional analysis of an alternative promoter of human intersectin 1 gene 
    Kropyvko, S.V.; Tsyba, L.O.; Skrypkina, I.Ya.; Rynditch, A.V. (Вiopolymers and Cell, 2010)
    Intersectin 1 (ITSN1) gene encodes an evolutionarily conserved adaptor protein that functions in clathrin-mediated endocytosis, cell signalling, apoptosis and cytoskeleton rearrangements. Its expression is characterized ...
  • Interactome of invadopodia scaffold protein TKS5 
    Kropyvko, S.V. (Вiopolymers and Cell, 2015)
    TKS5 is a scaffold protein that takes part in invadopodia functioning and reactive oxygen species (ROS) production. TKS5 is a critical component of invadopodia as its absence results in the loss of cancer cells ability to ...
  • ITSN protein family: regulation of diversity, role in signalling and pathology 
    Tsyba, L.O.; Dergai, M.V.; Skrypkina, I.Ya.; Nikolaienko, O.V.; Dergai, O.V.; Kropyvko, S.V.; Novokhatska, O.V.; Morderer, D.Ye.; Gryaznova, T.A.; Gubar, O.S.; Rynditch, A.V. (Вiopolymers and Cell, 2013)
    Adaptor/scaffold proteins of the intersectin (ITSN) family are important components of endocytic and signalling complexes. They coordinate trafficking events with actin cytoskeleton rearrangements and modulate the activity ...
  • New partners of TKS4 scaffold protein 
    Kropyvko, S.V. (Вiopolymers and Cell, 2015)
    TKS4 scaffold protein is involved in the formation of invadopodia, the production of reactive oxygen species (ROS) by tumor cells and other cellular processes. Aim. To identify new TKS4 partners involved in the actin ...
  • Transcriptional and posttranscriptional regulation of the adaptor/scaffold protein gene ITSN1 
    Kropyvko, S.V.; Gubar, O.S.; Gryaznova, T.A.; Morderer, D.Ye.; Gerasymchuk, D.O.; Syvak, L.A.; Grabovoy, A.N.; Rynditch, A.V. (Вiopolymers and Cell, 2016)
    ITSN1 adaptor/scaffold protein takes part in a variety of physiological and pathological cellular processes. It has a complex expression regulation and many protein partners. Aim. Characterization of the ITSN1 functioning ...